Nervous System

Nervous System

Introduction

·       The nervous system is the master control and communication system of the body.

·       It regulates and coordinates all voluntary and involuntary activities by transmitting electrical impulses between different parts of the body.

·       Unlike the endocrine system (which controls via hormones and is slower), the nervous system acts rapidly and precisely.

Key features

  • Receives information (sensory input) from internal and external environment.
  • Processes and interprets (integration) sensory input.
  • Sends commands (motor output) to effectors (muscles/glands).
  • Maintains homeostasis, behavior, learning, memory, emotions, and survival.

Divisions of the Nervous System

1. Anatomical Divisions

  • Central Nervous System (CNS)
    • Composed of Brain and Spinal Cord.
    • Acts as the command center: receives, integrates, and sends out instructions.
  • Peripheral Nervous System (PNS)
    • Includes cranial nerves (12 pairs) and spinal nerves (31 pairs).
    • Links CNS to body parts.
    • Subdivisions:
      • Somatic Nervous System (SNS): voluntary control of skeletal muscles.
      • Autonomic Nervous System (ANS): involuntary control of smooth muscles, cardiac muscle, glands.

2. Functional Divisions

  • Sensory (Afferent) Division: carries impulses from receptors → CNS.
  • Motor (Efferent) Division: carries impulses from CNS → effectors.

Functions of Nervous System

  1. Sensory Function: detect changes in internal/external environment via receptors.
  2. Integrative Function: analyze, interpret, and store sensory information; decide response.
  3. Motor Function: elicit responses via muscles (movement) or glands (secretion).
  4. Higher Functions: learning, memory, speech, emotions, consciousness, and behavior.

Neuron (Nerve Cell)

Structure

  • Cell Body (Soma/Perikaryon): nucleus, Nissl bodies (rough ER), cytoplasm.
  • Dendrites: branched processes, receive impulses.
  • Axon: single long process, conducts impulses away. Contains axoplasm and axolemma.
  • Myelin Sheath: insulating covering formed by Schwann cells (PNS) or oligodendrocytes (CNS).
  • Nodes of Ranvier: gaps in myelin, allow saltatory conduction (fast impulse).
  • Axon Terminals: synaptic end bulbs release neurotransmitters.

Classification

  1. Structural
    • Unipolar: one process (sensory neurons).
    • Bipolar: one dendrite, one axon (retina, olfactory).
    • Multipolar: many dendrites, one axon (motor neurons, interneurons).
  2. Functional
    • Sensory (Afferent) Neurons: transmit impulses from receptors → CNS.
    • Motor (Efferent) Neurons: transmit impulses from CNS → effectors.
    • Interneurons (Association Neurons): connect sensory and motor neurons in CNS.

Properties

  • Excitability: ability to respond to stimuli.
  • Conductivity: ability to transmit impulses.
  • Transmission: impulse passes across synapses via neurotransmitters.
  • Refractory Period: time during which neuron cannot be re-excited.

Brain – Structure and Functions

The brain (~1.4 kg, 2% body weight) is protected by the skull, meninges, and cerebrospinal fluid (CSF).

1. Cerebrum

  • Largest part, divided into two hemispheres connected by corpus callosum.
  • Has cerebral cortex (gray matter) and inner white matter.
  • Lobes & Functions:
    • Frontal: motor control, speech, reasoning, personality.
    • Parietal: sensory perception (touch, pain, temperature).
    • Temporal: hearing, memory, smell.
    • Occipital: vision.

2. Diencephalon

  • Thalamus: relay center for sensory impulses.
  • Hypothalamus: homeostasis, temperature regulation, hunger, thirst, circadian rhythm, endocrine control.

3. Brainstem

  • Midbrain: visual & auditory reflexes, motor pathways.
  • Pons: connects higher brain to spinal cord; respiration.
  • Medulla Oblongata: vital centers – heartbeat, respiration, blood pressure.

4. Cerebellum

  • Located posteriorly.
  • Functions: coordination of movement, balance, posture, muscle tone.

Spinal Cord – Structure and Functions

  • Extends from medulla oblongata → L1/L2 vertebra.
  • Protected by vertebrae, meninges, and CSF.
  • Gray Matter (H-shaped): contains neuron cell bodies.
  • White Matter: contains ascending (sensory) and descending (motor) tracts.
  • Functions:
    • Reflex center (spinal reflexes).
    • Pathway for conduction of impulses to/from brain.

Autonomic Nervous System (ANS)

Controls involuntary functions (smooth muscle, cardiac muscle, glands). Divided into:

1. Sympathetic Division (Fight or Flight)

  • Origin: thoracolumbar region (T1–L2).
  • Neurotransmitter: norepinephrine (mostly).
  • Effects:
    • ↑ Heart rate & blood pressure.
    • Dilates pupils.
    • Dilates bronchioles.
    • Inhibits digestion & urinary activity.
    • Mobilizes glucose and energy reserves.

2. Parasympathetic Division (Rest and Digest)

  • Origin: craniosacral region (cranial nerves III, VII, IX, X, and sacral nerves S2–S4).
  • Neurotransmitter: acetylcholine.
  • Effects:
    • ↓ Heart rate & blood pressure.
    • Constricts pupils.
    • Constricts bronchioles.
    • Stimulates digestion, salivation, and urination.
    • Conserves and restores body energy.

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