Vitamins & Minerals

VITAMINS & MINERALS

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·       Vitamins and minerals are essential nutrients required by the body in small amounts for various physiological functions, including growth, development, and maintenance of health.

·       They play crucial roles in numerous biochemical processes, including metabolism, immunity, and tissue repair.

·       Because the body cannot synthesize most vitamins and minerals, they must be obtained from the diet or supplements.

Definition

Vitamins are organic compounds that are necessary in small quantities for normal body function and growth. They are classified based on their solubility:

·        Fat-soluble vitamins: A, D, E, K

·        Water-soluble vitamins: B-complex (B1, B2, B3, B5, B6, B7, B9, B12) and Vitamin C

Minerals are inorganic elements that the body needs to function properly. They are divided into two categories:

·        Macrominerals: Calcium, Phosphorus, Potassium, Sulfur, Sodium, Chloride, Magnesium

·        Trace minerals: Iron, Manganese, Copper, Iodine, Zinc, Fluoride, Selenium

Classification

Vitamins

·        Fat-Soluble

o   Vitamin A: Essential for vision, immune function, and skin health. Found in carrots, sweet potatoes, and liver.

o   Vitamin D: Important for calcium absorption and bone health. Found in sunlight, fortified milk, and fatty fish.

o   Vitamin E: Acts as an antioxidant. Found in nuts, seeds, and green leafy vegetables.

o   Vitamin K: Crucial for blood clotting. Found in green leafy vegetables like spinach and kale.

·        Water-Soluble

o   Vitamin B1 (Thiamine): Supports energy metabolism. Found in whole grains, pork, and legumes.

o   Vitamin C: Important for the synthesis of collagen and acts as an antioxidant. Found in citrus fruits, strawberries, and bell peppers.

Minerals

·        Macrominerals

o   Calcium: Essential for bone health. Found in dairy products, leafy greens, and fortified foods.

o   Magnesium: Involved in over 300 biochemical reactions in the body. Found in nuts, seeds, and whole grains.

·        Trace Minerals

o   Iron: Necessary for oxygen transport in the blood. Found in red meat, beans, and fortified cereals.

o   Zinc: Important for immune function and wound healing. Found in meat, shellfish, and legumes.

Pharmacokinetics

·        Absorption: Fat-soluble vitamins are absorbed along with dietary fats in the small intestine, whereas water-soluble vitamins are absorbed directly into the bloodstream. Minerals are absorbed in the small intestine, with varying efficiencies depending on the mineral and the body's needs.

·        Distribution: After absorption, vitamins and minerals are distributed to various tissues where they are utilized for different metabolic processes. Fat-soluble vitamins are stored in body fat and the liver, while water-soluble vitamins are usually not stored and are excreted in the urine.

·        Metabolism: Vitamins generally undergo minimal metabolism, while some minerals may be converted into different forms within the body.

·        Excretion: Water-soluble vitamins are typically excreted via the urine when in excess, whereas fat-soluble vitamins are stored in the body, potentially leading to toxicity if consumed in large amounts. Excess minerals are excreted through urine, feces, and sweat.

Mechanism of Action

·        Vitamins: Act as coenzymes in metabolism (e.g., B vitamins in energy production), antioxidants (e.g., Vitamin C and E), and regulators of gene expression (e.g., Vitamin A).

·        Minerals: Serve as cofactors in enzymatic reactions (e.g., Zinc in DNA synthesis), structural components (e.g., Calcium in bones), and regulators of osmotic balance (e.g., Sodium and Potassium).

Uses

·        Preventing and treating deficiencies: Such as Vitamin D for rickets, Iron for anemia.

·        Supporting overall health: Multivitamins may be used to supplement dietary intake, especially in people with restricted diets.

·        Therapeutic uses: High-dose Vitamin C for boosting immunity, Magnesium for muscle cramps.

Adverse Effects

·        Fat-soluble vitamins: Hypervitaminosis A (liver damage), Hypervitaminosis D (hypercalcemia).

·        Water-soluble vitamins: Usually excreted, but high doses of Vitamin B6 can cause neuropathy.

·        Minerals: Excess Iron can cause organ damage, excessive Calcium can lead to kidney stones.

Contraindications

·        Vitamins: High doses of Vitamin A are contraindicated in pregnancy due to the risk of teratogenic effects.

·        Minerals: Calcium supplements may be contraindicated in patients with a history of kidney stones.

Role of the Nurse

1.     Assessment: Evaluate the patient's nutritional status, dietary intake, and potential deficiencies. Monitor for signs of toxicity or deficiency.

2.     Education: Instruct patients on the importance of a balanced diet, the appropriate use of supplements, and potential side effects of excessive supplementation.

3.     Administration: Ensure correct dosage and timing of supplements, particularly when administering fat-soluble vitamins or minerals that may interact with other medications.

4.     Monitoring: Regularly monitor blood levels of specific vitamins and minerals, especially in patients at risk for deficiencies or toxicities.

5.     Documentation: Keep accurate records of supplementation, patient responses, and any adverse effects or contraindications.

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