Vaginal Contraceptives

 VAGINAL CONTRACEPTIVES

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·       Vaginal contraceptives are a form of birth control used to prevent pregnancy.

·       These contraceptives are inserted into the vagina and work through various mechanisms to inhibit sperm from fertilizing an egg.

Definition

·       Vaginal contraceptives refer to methods of contraception that are administered via the vaginal route.

·       These include hormonal and non-hormonal methods designed to prevent pregnancy.

Classification

1.     Hormonal Vaginal Contraceptives:

o   Vaginal Rings:

§  Example: NuvaRing (etonogestrel/ethinyl estradiol)

o   Hormonal Gels:

§  Example: Phexxi (lactic acid, citric acid, and potassium bitartrate)

2.     Non-Hormonal Vaginal Contraceptives:

o   Spermicides:

§  Example: Nonoxynol-9

o   Barrier Methods:

§  Example: Diaphragms and Cervical Caps (e.g., FemCap)

Pharmacokinetics

Hormonal Vaginal Contraceptives:

·        Absorption: Hormones are absorbed through the vaginal mucosa.

·        Distribution: Hormones are distributed throughout the bloodstream.

·        Metabolism: Metabolized primarily in the liver.

·        Excretion: Metabolites are excreted via urine and feces.

Non-Hormonal Vaginal Contraceptives:

·        Absorption: Minimal systemic absorption; act locally.

·        Excretion: Residual compounds are washed out of the vagina naturally or during intercourse.

Mechanism of Action

Hormonal Vaginal Contraceptives:

·        Inhibit Ovulation: Prevent the release of an egg from the ovaries.

·        Thicken Cervical Mucus: Makes it difficult for sperm to enter the uterus.

·        Thin Endometrial Lining: Reduces the likelihood of implantation.

Non-Hormonal Vaginal Contraceptives:

·        Spermicides: Immobilize or kill sperm.

·        Barrier Methods: Physically block sperm from entering the uterus.

Uses

·        Contraception: Primary use to prevent pregnancy.

·        Regulation of Menstrual Cycles: Hormonal methods can help in regulating menstrual cycles.

·        Management of Menstrual Symptoms: Reduce symptoms such as heavy bleeding and menstrual pain.

Adverse Effects

Hormonal Vaginal Contraceptives:

·        Common: Vaginal irritation, discharge, and discomfort.

·        Serious: Increased risk of blood clots, stroke, and cardiovascular events.

Non-Hormonal Vaginal Contraceptives:

·        Common: Vaginal irritation and allergic reactions.

·        Serious: Increased risk of urinary tract infections (UTIs) and toxic shock syndrome (with diaphragms and cervical caps).

Contraindications

Hormonal Vaginal Contraceptives:

·        History of thromboembolic disorders.

·        Hormone-sensitive cancers (e.g., breast cancer).

·        Uncontrolled hypertension.

·        Liver disease.

Non-Hormonal Vaginal Contraceptives:

·        Allergy to components.

·        Abnormal vaginal anatomy that prevents proper placement.

Role of Nurse

·        Education: Educate patients on the proper use and insertion techniques of vaginal contraceptives.

·        Assessment: Assess patient suitability for vaginal contraceptives, considering medical history and contraindications.

·        Monitoring: Monitor for adverse effects and provide guidance on managing any complications.

·        Counseling: Counsel patients on various contraceptive options, helping them make informed decisions.

·        Support: Provide emotional support and address concerns or misconceptions about vaginal contraceptives.

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